CONFIDENTIAL CLINICAL ADVISORY MATERIALS

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CLINICAL ADVISORY BRIEF

What children can't say,
Lumily listens.

No one is building continuous health monitoring for children — so we are. Parents leave the hospital after surgery with a discharge sheet and a prayer. They don't know what to watch for. Children with nonverbal disabilities can never say "something hurts." And in otherwise healthy kids, hidden conditions go undetected until something goes terribly wrong. Lumily is a wrist-worn pediatric wearable — the first of its kind for ages 1 to 18 — with medical-grade biosensing and the only Nonverbal Distress Index ever built for children. A night light in the dark: real-time monitoring that alerts parents when something shifts, and passes that data directly to their child's care team.

Let's Talk

The Problem

Children are dying from
what we could catch earlier.

Pediatric sepsis alone kills nearly 1,900 children per year in the U.S. — and it's involved in nearly 1 in 5 pediatric in-hospital deaths. Our north star: reduce readmission rates by giving parents and providers continuous visibility into what's happening between visits. For all children — and especially for those who can't speak for themselves.

18,000+

pediatric sepsis cases per year in the U.S.

JAMA · March 2026

1 in 5

pediatric in-hospital deaths involve sepsis

JAMA · March 2026

Zero

pediatric-specific health wearables exist today

Univ. of Pacific · 2025

What We're Building

V1Every family

Continuous health monitoring for all children ages 1–18. Heart rate, respiratory rate, temperature, SpO2, sleep quality, and GPS safety tracking — all feeding into a family app that gives parents objective data and peace of mind between well visits.

V2Nonverbal & special needs

1.5 million children with autism, cerebral palsy, Angelman syndrome, and other conditions who will never be able to report pain, illness, or distress. The Nonverbal Distress Index was built specifically for them.

V3Clinical & post-discharge

Sepsis early warning. Post-surgical monitoring. Post-viral cardiac watch. Return-to-sport clearance. Epic/EHR integration with a physician-facing dashboard — so providers see continuous data in their existing workflow, not another portal. The critical window after discharge when parents are on their own — and when readmissions happen.

You've Seen This

These are your patients.
These are your 2am calls.

Every one of these is a moment where continuous monitoring would change the outcome — for the child, for the parent, and for you.

The post-op parent calling at 2am

"His breathing sounds weird. I don't know if it's normal." Mom is alone. You can't see what she's seeing. You tell her to watch and call back — because there's nothing else you can do. With Lumily, you'd already have her child's respiratory rate, heart rate, and SpO2 trending on your dashboard.

The child who can't tell you about last night

Your Angelman patient comes in for a routine visit. Mom thinks he had a seizure last night but isn't sure — he can't tell her. You check vitals, everything looks fine now. But you're flying blind on what happened 12 hours ago. With Lumily, you'd see the accelerometer spike, the heart rate surge, the EDA activation — time-stamped and waiting in the chart.

The fever that spiked 6 hours too late

Post-chemo, immunocompromised. Mom checks his forehead at bedtime — feels warm but "probably fine." By 4am it's 104° and they're in the ER. Febrile neutropenia. With Lumily, continuous skin temperature would have flagged the upward trend 5–12 hours earlier — before it became an emergency.

The "healthy" kid who wasn't

Thirteen-year-old athlete. Passed his sports physical. Collapsed at practice. Undiagnosed HCM. The family never knew. With Lumily, continuous heart rate monitoring during exertion would have flagged an abnormal cardiac pattern weeks before — turning a tragedy into a referral.

The post-viral kid who "seemed fine"

Flu resolved 5 days ago. Kid's back at school. But two weeks later — myocarditis. The inflammation was building silently the whole time. With Lumily, post-viral cardiac watch auto-activates when fever resolves — tracking HRV and heart rate for the exact window when myocarditis risk peaks.

This is why we need you.

You know these patients. You live these calls. Help us build the thing that changes what happens next.

What Lumily Does

Every sensor has
a clinical purpose.

One wrist-worn device. Six sensor types. Each one maps directly to a clinical outcome that matters to you and the families you serve.

PPG (Photoplethysmography)

Heart Rate · HRV · SpO2

Cardiac safety alerts — exertion ceiling for HCM, LQTS, POTS, WPW

Post-viral cardiac watch — auto-activates when fever resolves (myocarditis risk)

Sleep apnea screening — SpO2 desaturation + respiratory effort proxy

Sepsis early warning — HR + HRV suppression as convergence signal

EDA / Galvanic Skin Response

Autonomic Stress

Nonverbal Distress Index — core signal for detecting pain in nonverbal children

Panic precursor detection — 83% precision, 2–5 min before peak distress (JMIR 2025)

Chronic anxiety biomarker — long-term HRV + EDA trending

Skin Temperature

Continuous Thermometry

Febrile neutropenia — 5–12h earlier fever detection vs. oral thermometry (Ped Blood Cancer 2022)

Illness convergence — temperature + HR + RR trending together = early warning

Post-viral monitoring trigger — fever resolution activates cardiac watch

Accelerometer + Gyroscope

Motion · Stillness · Patterns

Seizure-pattern proxy — repetitive motion detection (Angelman, Rett, epilepsy)

Movement suppression — stillness that isn't sleep as NDI distress signal

ADHD medication tracking — objective activity data vs. subjective parent report

Respiratory Rate

PPG-Derived Breathing

Asthma exacerbation — RR elevation 6–12h before child reports difficulty breathing

Sepsis convergence signal — RR + HR + temp + HRV shifting together

Sealed Microphone

Acoustic Monitoring

Cystic fibrosis — continuous cough frequency, duration, and character logging

Wheeze detection — asthma exacerbation confirmation layer

The Nonverbal Distress Index

All six sensors feed into the NDI — a per-child calibrated algorithm that learns each child's unique physiological baseline over 7–14 days and alerts when multiple signals diverge simultaneously. Not a diagnosis. A reliable tap on the shoulder. Nothing like this exists.

Patent Pending — Nonverbal Distress Index

Patent Pending — Multi-Signal Convergence Detection

Why Now

This is the ground floor.

This couldn't have been built five years ago. Today, it can — and no one else is doing it.

The timing is right

The JAMA pediatric sepsis study just published in March 2026. Wearable sensor technology is finally small, accurate, and affordable enough for children. FDA De Novo pathways exist for novel pediatric devices. The science, the tech, and the regulatory path have all converged — right now.

First mover. Your name on it.

This is the first clinical advisory board for the first pediatric health wearable. Co-authorship on the validation studies. Your name on the foundational research. The physicians who help build this will be cited for decades. This is legacy-defining work.

It solves your problem too

You're flying blind between visits. Parents call with anxiety you can't address from a phone call. You make decisions based on a 15-minute snapshot. Lumily gives you continuous, objective data on your patients — between visits, after discharge, during recovery. This isn't just for parents. It's for you.

How You Can Help

We need pediatricians
to build this right.

Lumily is pre-launch and actively forming its clinical advisory board. We're looking for pediatricians across specialties — general peds, cardiology, neurology, pulmonology, oncology — who want to shape how continuous monitoring works for children.

Alert Threshold Design

Validate clinically safe, age-appropriate thresholds for every detection capability. Your expertise prevents alert fatigue and ensures the right signals reach caregivers at the right time.

Clinical Validation Study

Co-design the validation studies at VCU and UVA. Participate as investigator. Co-author the publications. Help build the evidence base that earns FDA clearance.

Protocol Development

Design post-discharge monitoring plans, return-to-sport protocols, and physician-facing dashboards that fit real clinical workflows — not theoretical ones.

Network & Credibility

Introductions to specialists at VCU, UVA, and beyond. Hospital pilot identification. Clinical credibility for FDA conversations and grant applications.

What it looks like

Monthly calls (30–60 min) + async protocol review. Equity-based compensation. Structured entirely around your schedule.

The Founder

Lauren Thacker

FOUNDER & CEO · BRIGHT MANTLE HOLDINGS

Lauren lives this problem. She navigates the medical system daily with an autoimmune disorder, POTS, EDS, and other complex conditions — often with little information and even less guidance. Her daughter has sensory processing disorder, is tilting toward EDS herself, and gets sick more often than most kids. Lauren has spent a thousand nights awake, alone, worried — and cried through too many of them. But the more mothers she talked to, the more she heard the same thing: "I wish I had something like that." That's why she's here. Lumily exists because no parent should have to guess whether their child is okay.

A BRIGHT MANTLE HOLDINGS COMPANY

Let's have a conversation.

No commitment. No pitch deck. Just a conversation about what continuous pediatric health monitoring could look like — and whether you'd want to help shape it.